Research assessing EID risk has typically focused on identifying geographic regions and wildlife species whereby spillover of zoonotic diseases into humans is most likely. The threat of emerging infectious diseases (EIDs) to wildlife health and biodiversity conservation is recognized, but cross-species transmission of novel pathogens, or spillover, is typically viewed in the specific context of originating in a wildlife reservoir and transmitting to humans. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. Funding for DGS was provided by a Wellcome Trust Senior Research Fellowship (217221/Z/19/Z). Funding for DTSH was provided by a Royal Society Te Aparangi grant RDF-MAU1701. The work is made available under the Creative Commons CC0 public domain dedication.įunding: This work was supported in part by the USGS John Wesley Powell Center for Analysis and Synthesis, National Institute of Allergy and Infectious Diseases of the National Institutes of Health (Award Number R01AI110964), and the US Department of Defense, Defense Threat Reduction Agency (HDTRA11710064). This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. PLoS Pathog 16(9):Įditor: Seema Lakdawala, University of Pittsburgh, UNITED STATES (2020) Possibility for reverse zoonotic transmission of SARS-CoV-2 to free-ranging wildlife: A case study of bats. We highlight an urgent need to proactively connect the wellbeing of human and wildlife health during the current pandemic and to implement new tools to continue wildlife research while avoiding potentially severe health and conservation impacts of SARS-CoV-2 "spilling back" into free-ranging bat populations.Ĭitation: Olival KJ, Cryan PM, Amman BR, Baric RS, Blehert DS, Brook CE, et al. Our review of the global distribution and host range of β-CoV evolutionary lineages suggests that 40+ species of temperate-zone North American bats could be immunologically naïve and susceptible to infection by SARS-CoV-2. Here, we review the diversity and natural host range of β-CoVs in bats and examine the risk of humans inadvertently infecting free-ranging bats with SARS-CoV-2. Given the likely bat origin of SARS-CoV-2 and related beta-coronaviruses (β-CoVs), free-ranging bats are a key group of concern for spillover from humans back to wildlife. ![]() The establishment of new wildlife reservoirs for SARS-CoV-2 would further complicate public health control measures and could lead to wildlife health and conservation impacts. Widespread human transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) also presents a new set of challenges when considering viral spillover from people to naïve wildlife and other animal populations. The COVID-19 pandemic highlights the substantial public health, economic, and societal consequences of virus spillover from a wildlife reservoir.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |